September 18, 2011
- Cedarwood Essential Oils Studied for Anti-Cancer Effects
Cedarwood Essential Oils Studied for Anti-Cancer Effects
Pubmed.gov continues to provide a wealth of information regarding the anti-cancer potential of essential oils. In this study, several species of Cedarwood were evaluated for their efficacy in eradicating the K562 cell line, which is a variety of leukemia. Of the cedarwood oils mentioned, Ananda carriers Moroccan Atlatic Cedarwood, and may carry Himalayan Cedarwood in the future.
While again actual usage protocols are a long ways off (and whether pharmaceutical companies would ever pay to have this research forwarded is another matter :) -- it is interesting that the number of essential oils showing anti-cancer properties continues to grow.
These now include, at minimum: Frankincense, Lemongrass, Coriander, Lavender, Sandalwood, and others (should you wish to browse PubMed.gov and search for 'essential oil cancer', you can find more of these yourself.
Title: In vitro evaluation of the anti-proliferative activities of the wood essential oils of three Cedrus species against K562 human chronic myelogenous leukaemia cells.
By: Saab AM, Lampronti I, Borgatti M, Finotti A, Harb F, Safi S, Gambari R.
Section of Molecular Biology, Department of Biochemistry and Molecular Biology , University of Ferrara , Via Fossato di Mortara 74 , 1-44121 Ferrara , Italy.
Published in: Nat Prod Res. 2011 Dec 14
Abstract: There are four kinds of Cedar: Cedrus libani naturally occurring in Lebanon, Syria and Turkey, Cedrus atlantica in Morocco and Algeria, Cedrus brevefolia in Cyprus Island and Cedrus deodara which is distributed in Himalayan Mountains. Wood essential oils obtained from C. libani, C. atlantica and C. deodara were tested for the inhibition of K562 cell proliferation and for the induction of erythroid differentiation. The wood essential oils of C. libani, C. atlantica and C. deodara inhibited the proliferation of the K562 cell line exhibiting IC(50) values 23.38 ± 1.7, 59.37 ± 2.6 and 37.09 ± 1.4 µg mL(-1), respectively. Meanwhile, C. libani wood oils induced a percentage of erythroid differentiation of 15 ± 2% at concentration 5 µg mL(-1). Cedrus deodara wood oil indicated a percentage of erythroid differentiation of 20 ± 2% at concentration 25 µg mL(-1) and C. atlantica wood oils showed a percentage of erythroid differentiation of 12 ± 1.8% at concentration 10 µg mL(-1).
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