• Esters
• Neryl acetate
• Helichrysum italicum grown on the island of Corsica has the highest levels of this compound, known for its therapeutic value for healing and rejuvenating the skin. Also known to promote calm and clear the mind.
• Ketones
• Helichrysum italicum is the only essential oil known to contain di-ketones. While typically ketones found in essential oils are of a harmful nature (they often cause unchecked cell proliferation, i.e. tumors), the dichotic nature of these molecules provide helichrysum with much of its powerful regenerative effects, stimulating new, healthy cells. Because the di-ketones are only found in Helichrysum italicum, specifically varieties found on the island of Corsica, they are also referred to as italidones. Italidones are recognized for their incredible ability to regenerate tissue and promote cell turnover, leading to increased healing.
• The italidiones are also attributed to providing the oil with its spiritual healing benefits, healing old emotional wounds.
• Sesquiterpenes
• Alpha, beta, and gamma-curcumenes
• The curcumenes, particularly Υ-curcumene, are well known for their anti-inflammatory effects, which in turn translates into the notorious pain-relieving effects produced by helichrysum.
• It appears to be the curcumenes that provide the turmeric, or curry-like, fragrance as well as much of the tissue healing benefits. Turmeric is well known for its anti-inflammatory properties, and it is this same component that likely lends the same characteristics in helichrysum.
• Italicene, b-caropyllene, rosifoliol
• Monoterpenes
• b-pinene
• This compound has been found to be a potent scavenger of free radicals
• α-pinene, limonene
• Oxide
• 1,8-cineole
• Alcohols
• Linalool, geraniol, nerol
• Phenol
• Eugenol

An example of typical Mediterranean helichrysum plant chemistry is as follows: α-pinene, b-pinene, myrcene, camphene, limonene, eugenol, 1,8-cineole, terpinen-4-ol, linalool, neryl acetate, italidone, geraniol, nerol and several other b-diketones.